Selected Publications: (Please click publication text to learn more)

Dimitrova, D. I., Reichenbach, N. L., Yang, X., Pfleiderer, W., Charubala, R., Gaughan, J. P., Suh, B., Henderson, E. E., Suhadolnik, R. J., and Rogers, T. J. (2007) Inhibition of HIV Type 1 Replication in CD4+ and CD14+ Cells Purified from HIV Type 1-Infected Individuals by the 2-5A Agonist Immunomodulator, 2-5AN6B, AIDS Research and Human Retroviruses 23: 123-134.

Dimitrova, D. I., Yang, X., Reichenbach, N. L., Karakasidis, S., Sutton, R. E., Henderson, E. E., Rogers, T. J., Suhadolnik, R. J. (2005) Lentivirus-Mediated Transduction of PKR into CD34+ Hematopoietic Stem Cells Inhibits HIV-1 Replication in Differentiated T Cell Progeny, J Interferon & Cytokine Res 25: 345-360.

Suhadolnik, R. J., Peterson, D. L., Reichenbach, N. L., Roen, G., Metzger, M., McCahan, J., O’Brien, K., Welsch, S., Gabriel, J., Gaughan, J. P., McGregor, N. R. (2004) Clinical and Biochemical Characteristics Differentiating Chronic Fatigue Syndrome from Major Depression and Healthy Control Populations: Relation to Dysfunction of the RNase L Pathway, J Chronic Fatigue Syndrome 12: 5-35.

Charubala, R., Pfleiderer, W., Suhadolnik, R. J., Iacono, K. T., Muto, N. F., Homan, J. W., Martinand-Mari, C., Horvath, S. E., Henderson, E. E., Steele, A., Rogers, T. J. (2002) Inhibition of HIV-1 Replication by Chemically Synthesized, Nuclease-Resistant, Nontoxic (2’-5’)-Oligoadenylate Agonists, Helv Chimica Acta 85: 2284-2299.

Homan, J. W., Steele, A., Martinand-Mari, C., Reichenbach, N. L., Rogers, T. J., Henderson, E. E., Charubala, R., Pfleiderer, W., and Suhadolnik, R. J. (2002) Inhibition of Morphine-potentiated HIV-1 Replication in Peripheral Blood Mononuclear Cells with a Stable 2-5A Agonist Analog, 2-5AN6B. Journal of Acquired Immune Deficiency Syndromes 30: 9-20.

Shetzline, S. E, Martinand-Mari, C., Reichenbach, N. L., Buletic, Z., Lebleu, B., Pfleiderer, W., Charubala, R., De Meirleir, K., De Becker, P., Peterson, D. L., Herst, C. V. T., Englebienne, P., and Suhadolnik, R. J. (2002) Structural and Functional Features of the 37 kDa 2-5A-dependent RNase L in Chronic Fatigue Syndrome. The Journal of Interferon & Cytokine Research 22: 443-456.

Shetzline, S.E., and Suhadolnik, R.J. (2001) Characterization of a 2',5'-Oligoadenylate (2-5A)-dependent 37-kDa RNase L. Azido Photoaffinity Labeling and 2-5A-Dependent Activation. The Journal of Biological Chemistry 276: 23707-23711.

Adelson, M. E., Martinand-Mari, C., Iacono, K. T., and Suhadolnik, R. J. (1999) Inhibition of Human Immunodeficiency Virus (HIV-1) Replication in SupT1 Cells Transduced with a HIV-1 LTR-driven PKR cDNA Construct. The European Journal of Biochemistry 264: 806-815.

Muto, N. F., Martinand-Mari, C., Adelson, M. E., and Suhadolnik, R. J. (1999) Inhibition of Replication of Reactivated Human Immunodeficiency Virus Type 1 in Latently-Infected U1 Cells Transduced with an HIV-1 LTR-driven PKR cDNA Construct. The Journal of Virology 73: 9021-9028.

Schirmeister-Tichy, H., Iacono, K. T., Muto, N. F., Homan, J. W., Suhadolnik, R. J., and Pfleiderer, W. (1999) Synthesis, Characterization and Biological Activities of New Potential Antiviral Agents - (2'-5')Adenylate Trimer Analogs Containing 3'-Deoxy-3'-(hexadecanoylamino)-adenosine at the 2'-Terminus. Helvetica Chimica Acta 82: 597-613.

Suhadolnik, R. J., Peterson, D. L., O'Brien, K., Cheney, P. R., Herst, C. V. T., Reichenbach, N. L., Kon, N., Horvath, S. E., Iacono, K. T., Adelson, M. E., De Meirleir, K., De Becker, P., Charubala, R., and Pfleiderer, W. (1997) Evidence for a Novel Low Molecular Weight RNase L in Chronic Fatigue Syndrome. The Journal of Interferon & Cytokine Research 17: 377-385.

Kon, N., and Suhadolnik, R. J. (1996) Identification of the ATP Binding Domain of Recombinant, Human 40 kDa 2-5A Synthetase by Photoaffinity Labeling with [ -32P]8-AzidoATP. The Journal of Biological Chemistry 271: 1983-1990.